Sphincter preservation in anal cancer: A brief review

Management of anal cancer is a challenge.The goal of treatment is to eradicate tumor without sacrificing the anal sphincters.The idea of organ preservation emerged following the discovery of a high complete response rate from preoperative combined Scarface Dress chemoradiation (CRT) prior to abdominoperineal resection.CRT is widely accepted as the

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Oxalate disrupts monocyte and macrophage cellular function via Interleukin-10 and mitochondrial reactive oxygen species (ROS) signaling

Oxalate is a small compound found in certain plant-derived foods and is a major component of calcium oxalate (CaOx) kidney stones.Individuals that consume oxalate enriched meals have an increased risk of forming urinary crystals, which are precursors to CaOx kidney stones.We previously reported that a single dietary oxalate load induces nanocrystal

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